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Does CBD oil work against anxiety?

Every year more and more people suffer from some form of anxiety disorder. Since they mostly prefer to avoid taking heavy medication, many people search for natural alternatives and come across a promising substance: CBD.

What is anxiety and how is it medically treated?

Anxiety is a survival mechanism that plays a key role in evolution. However, excessive or constant anxiety can be a major burden and can lead to limitations in everyday life.

Anxiety symptoms occur in a number of neuropsychiatric disorders, including generalized anxiety disorder, panic disorder, and social anxiety disorder. Anxiety-like conditions also occur in obsessive-compulsive disorder and post-traumatic stress disorder.

These anxiety disorders often cause a reduction in a subjective sense of well-being, an increased risk of unemployment, relationship problems and an increased risk of suicide.

Pharmacological treatments include serotonin reuptake inhibitors, serotonin noradrenalin reuptake inhibitors, benzodiazepines (benzos), monoamine oxidase inhibitors, tricyclic antidepressants, and 5-hydroxytryptamine (5-HT) 1A receptor agonists.

What is CBD and CBD oil?

Cannabidiol (CBD) is one of 113 identified active cannabinoids derived from the cannabis plant.

Although more and more physicians acknowledge the therapeutic effect of CBD, there is still confusion about the promising cannabinoid in terms of mode of action, legality and correct dosage.

Most users buy CBD as an over-the-counter CBD oil classified as a dietary supplement.

By activating the body’s own receptors, CBD can help with a variety of health problems. Many users report the positive effect of CBD oil on anxiety and/or anxiety disorders. In the following section, you can read exactly how the therapeutic effect is produced.

How exactly does CBD oil work against anxiety according to studies?

CBD has a broad pharmacological spectrum, including interactions with multiple receptors that are known to regulate anxiety and other anxiety like states.

These include in particular the cannabinoid type 1 receptor (CB1), the serotonin 5-HT1A receptor and the transient receptor potential cation channel of subfamily V, subtype 1.

In addition, CBD can also directly or indirectly regulate the peroxisome proliferator-activated receptor γ, the orphan G protein-coupled receptor 55, the equilibrated nucleoside transporter, the adenosine transporter, additional TRP channels, and glycine receptors.

The effect of CBD oil against anxiety disorders has therefore been proven by scientific studies.

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Does CBD oil work against anxiety? 2

Human studies show how CBD reduces anxiety.

Brazilian researchers conducted a small double-blind study in patients with general social anxiety.

After using CBD, participants reported a significant decrease in anxiety. The researchers validated the patients’ subjective reports by performing brain scans that showed cerebral blood flow patterns consistent with an anti-anxiety effect.

In another small study, researchers conducted a simulated public speech test on patients suffering from a social anxiety disorder.

Participants reported significantly fewer anxiety states supported by objective anxiety indicators such as heart rate and blood pressure.

The researchers concluded that the patients who had taken CBD were less anxious than those in the control group.

CBD oil for anxiety and other medications

Since there may be interactions between CBD and other medications, it is highly recommended that you discuss possible side effects with your doctor before taking CBD.

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